HIF1α regulates glioma chemosensitivity through the transformation between differentiation and dedifferentiation in various oxygen levels

Chemotherapy plays a significant role in glioma treatment; however, it has limited effectiveness in extending the life expectancies of glioma patients. Traditional studies have attributed this lack of efficacy to glioma stem cells (GSCs) and their high resistance to chemotherapy, and hypoxia worsens...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Wan, Wenwu, Xiong, Shuanglong, Wang, Junwei, Zou, Dewei, Lan, Chuan, Yu, Shuangjiang, Liao, Bin, Feng, Hua, Wu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554160/
https://www.ncbi.nlm.nih.gov/pubmed/28801626
http://dx.doi.org/10.1038/s41598-017-06086-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554160/
https://www.ncbi.nlm.nih.gov/pubmed/28801626
http://dx.doi.org/10.1038/s41598-017-06086-2

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