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HIF1α regulates glioma chemosensitivity through the transformation between differentiation and dedifferentiation in various oxygen levels
Chemotherapy plays a significant role in glioma treatment; however, it has limited effectiveness in extending the life expectancies of glioma patients. Traditional studies have attributed this lack of efficacy to glioma stem cells (GSCs) and their high resistance to chemotherapy, and hypoxia worsens...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554160/ https://www.ncbi.nlm.nih.gov/pubmed/28801626 http://dx.doi.org/10.1038/s41598-017-06086-2 |