Cargando…

Chronic Intermittent Hypobaric Hypoxia Improves Cardiac Function through Inhibition of Endoplasmic Reticulum Stress

We investigated the role of endoplasmic reticulum stress (ERS) in chronic intermittent hypobaric hypoxia (CIHH)-induced cardiac protection. Adult male Sprague-Dawley rats were exposed to CIHH treatment simulating 5000 m altitude for 28 days, 6 hours per day. The heart was isolated and perfused with...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Fang, Zhang, Li, Li, Yan-Qing, Teng, Xu, Tian, Si-Yu, Wang, Xiao-Ran, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554163/
https://www.ncbi.nlm.nih.gov/pubmed/28801645
http://dx.doi.org/10.1038/s41598-017-08388-x