Protein O-mannosylation deficiency increases LprG-associated lipoarabinomannan release by Mycobacterium tuberculosis and enhances the TLR2-associated inflammatory response

Protein O-mannosylation is crucial for the biology of Mycobacterium tuberculosis but the key mannosylated protein(s) involved and its(their) underlying function(s) remain unknown. Here, we demonstrated that the M. tuberculosis mutant (Δpmt) deficient for protein O-mannosylation exhibits enhanced rel...

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Detalles Bibliográficos
Autores principales: Alonso, Henar, Parra, Julien, Malaga, Wladimir, Payros, Delphine, Liu, Chia-Fang, Berrone, Céline, Robert, Camille, Meunier, Etienne, Burlet-Schiltz, Odile, Rivière, Michel, Guilhot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554173/
https://www.ncbi.nlm.nih.gov/pubmed/28801649
http://dx.doi.org/10.1038/s41598-017-08489-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554173/
https://www.ncbi.nlm.nih.gov/pubmed/28801649
http://dx.doi.org/10.1038/s41598-017-08489-7

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