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SNAP-25 phosphorylation at Ser187 regulates synaptic facilitation and short-term plasticity in an age-dependent manner

Neurotransmitter release is mediated by the SNARE complex, but the role of its phosphorylation has scarcely been elucidated. Although PKC activators are known to facilitate synaptic transmission, there has been a heated debate on whether PKC mediates facilitation of neurotransmitter release through...

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Detalles Bibliográficos
Autores principales: Katayama, Norikazu, Yamamori, Saori, Fukaya, Masahiro, Kobayashi, Shizuka, Watanabe, Masahiko, Takahashi, Masami, Manabe, Toshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554206/
https://www.ncbi.nlm.nih.gov/pubmed/28801590
http://dx.doi.org/10.1038/s41598-017-08237-x