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CREB3L2-mediated expression of Sec23A/Sec24D is involved in hepatic stellate cell activation through ER-Golgi transport

Hepatic fibrosis is caused by exaggerated wound healing response to chronic injury, which eventually leads to hepatic cirrhosis. Differentiation of hepatic stellate cells (HSCs) to myofibroblast-like cells by inflammatory cytokines is the critical step in fibrosis. This step is accompanied by enlarg...

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Detalles Bibliográficos
Autores principales: Tomoishi, Shotaro, Fukushima, Shinichi, Shinohara, Kentaro, Katada, Toshiaki, Saito, Kota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554210/
https://www.ncbi.nlm.nih.gov/pubmed/28801610
http://dx.doi.org/10.1038/s41598-017-08703-6