Ca(V)1.3 L-type Ca(2+) channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na(+) current

The spontaneous activity of sinoatrial node (SAN) pacemaker cells is generated by a functional interplay between the activity of ionic currents of the plasma membrane and intracellular Ca(2+) dynamics. The molecular correlate of a dihydropyridine (DHP)-sensitive sustained inward Na(+) current (I (st...

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Detalles Bibliográficos
Autores principales: Toyoda, Futoshi, Mesirca, Pietro, Dubel, Stefan, Ding, Wei-Guang, Striessnig, Joerg, Mangoni, Matteo E., Matsuura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554211/
https://www.ncbi.nlm.nih.gov/pubmed/28801600
http://dx.doi.org/10.1038/s41598-017-08191-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554211/
https://www.ncbi.nlm.nih.gov/pubmed/28801600
http://dx.doi.org/10.1038/s41598-017-08191-8

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