A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy

Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors. We examined the renoprotective effects of Ly, a novel non-steroidal mineralocorticoid receptor (MR) blocker, through two experimenta...

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Detalles Bibliográficos
Autores principales: Fujihara, Clarice K., Kowala, M. C., Breyer, M. D., Sena, Claudia R., Rodrigues, Mariliza V., Arias, Simone C. A., Fanelli, Camilla, Malheiros, Denise M., Jadhav, P. K., Montrose-Rafizadeh, Chahrzad, Krieger, Jose E., Zatz, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554220/
https://www.ncbi.nlm.nih.gov/pubmed/28801620
http://dx.doi.org/10.1038/s41598-017-08383-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554220/
https://www.ncbi.nlm.nih.gov/pubmed/28801620
http://dx.doi.org/10.1038/s41598-017-08383-2

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