Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway

Methylglyoxal (MG) accumulation has been observed in human cerebrospinal fluid and body tissues under hyperglycaemic conditions. Recent research has demonstrated that MG-induces neuronal cell apoptosis, which promotes the development of diabetic encephalopathy. Our previous animal study has shown th...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Huang, Jie, Zheng, Xian, Yang, Xia, Ding, Yan, Fang, Tongyong, Zhang, Yuyun, Wang, Shuaishuai, Zhang, Xiaofei, Luo, Xuan, Guo, Anlei, Newell, Kelly A., Yu, Yinghua, Huang, Xu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554232/
https://www.ncbi.nlm.nih.gov/pubmed/28801605
http://dx.doi.org/10.1038/s41598-017-08204-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554232/
https://www.ncbi.nlm.nih.gov/pubmed/28801605
http://dx.doi.org/10.1038/s41598-017-08204-6

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