Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer

P-glycoprotein (P-gp) is a drug transporter that effluxes chemotherapeutic drugs and is implicated in the development of resistance of cancer cells to chemotherapeutic drugs. To date, no drug has been approved to inhibit P-gp and restore chemotherapy efficacy. Moreover, majority of the reported inhi...

Descripción completa

Detalles Bibliográficos
Autores principales: Syed, Safiulla Basha, Arya, Hemant, Fu, I-Hsuan, Yeh, Teng-Kuang, Periyasamy, Latha, Hsieh, Hsing-Pang, Coumar, Mohane Selvaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554262/
https://www.ncbi.nlm.nih.gov/pubmed/28801675
http://dx.doi.org/10.1038/s41598-017-08062-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554262/
https://www.ncbi.nlm.nih.gov/pubmed/28801675
http://dx.doi.org/10.1038/s41598-017-08062-2

Ejemplares similares