Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance

BACKGROUND: Identification of genes whose basal mRNA expression predicts the sensitivity of tumor cells to cytotoxic treatments can play an important role in individualized cancer medicine. It enables detailed characterization of the mechanism of action of drugs. Furthermore, screening the expressio...

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Detalles Bibliográficos
Autores principales: Emad, Amin, Cairns, Junmei, Kalari, Krishna R., Wang, Liewei, Sinha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554409/
https://www.ncbi.nlm.nih.gov/pubmed/28800781
http://dx.doi.org/10.1186/s13059-017-1282-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554409/
https://www.ncbi.nlm.nih.gov/pubmed/28800781
http://dx.doi.org/10.1186/s13059-017-1282-3

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