Cancer progression by reprogrammed BCAA metabolism in myeloid leukemia

Reprogrammed cellular metabolism is a common characteristic observed in various cancers(1,2). However, whether metabolic changes directly regulate cancer development and progression remains poorly understood. Here we show that BCAT1, a cytosolic aminotransferase for the branched-chain amino acids (B...

Descripción completa

Detalles Bibliográficos
Autores principales: Hattori, Ayuna, Tsunoda, Makoto, Konuma, Takaaki, Kobayashi, Masayuki, Nagy, Tamas, Glushka, John, Tayyari, Fariba, McSkimming, Daniel, Kannan, Natarajan, Tojo, Arinobu, Edison, Arthur S., Ito, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554449/
https://www.ncbi.nlm.nih.gov/pubmed/28514443
http://dx.doi.org/10.1038/nature22314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554449/
https://www.ncbi.nlm.nih.gov/pubmed/28514443
http://dx.doi.org/10.1038/nature22314

Ejemplares similares