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Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response to Moraxella catarrhalis Proteins

Moraxella catarrhalis (Mcat) is a prominent mucosal pathogen causing acute otitis media (AOM). We studied Mcat nasopharyngeal (NP) colonization, AOM frequency and mucosal antibody responses to four vaccine candidate Mcat proteins: outer membrane protein (OMP) CD, oligopeptide permease (Opp) A, hemag...

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Detalles Bibliográficos
Autores principales: Ren, Dabin, Murphy, Timothy F., Lafontaine, Eric R., Pichichero, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554491/
https://www.ncbi.nlm.nih.gov/pubmed/28848555
http://dx.doi.org/10.3389/fimmu.2017.00953