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H-Ras Exerts Opposing Effects on Type I Interferon Responses Depending on Its Activation Status
Using shRNA high-throughput screening, we identified H-Ras as a regulator of antiviral activity, whose depletion could enhance Sindbis virus replication. Further analyses indicated that depletion of H-Ras results in a robust increase in vesicular stomatitis virus infection and a decrease in Sendai v...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554495/ https://www.ncbi.nlm.nih.gov/pubmed/28848563 http://dx.doi.org/10.3389/fimmu.2017.00972 |