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Impact of Alternative Splicing on the Human Proteome

Alternative splicing is a critical determinant of genome complexity and, by implication, is assumed to engender proteomic diversity. This notion has not been experimentally tested in a targeted, quantitative manner. Here, we have developed an integrative approach to ask whether perturbations in mRNA...

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Detalles Bibliográficos
Autores principales: Liu, Yansheng, Gonzàlez-Porta, Mar, Santos, Sergio, Brazma, Alvis, Marioni, John C., Aebersold, Ruedi, Venkitaraman, Ashok R., Wickramasinghe, Vihandha O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554779/
https://www.ncbi.nlm.nih.gov/pubmed/28768205
http://dx.doi.org/10.1016/j.celrep.2017.07.025