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Impact of Alternative Splicing on the Human Proteome
Alternative splicing is a critical determinant of genome complexity and, by implication, is assumed to engender proteomic diversity. This notion has not been experimentally tested in a targeted, quantitative manner. Here, we have developed an integrative approach to ask whether perturbations in mRNA...
Autores principales: | Liu, Yansheng, Gonzàlez-Porta, Mar, Santos, Sergio, Brazma, Alvis, Marioni, John C., Aebersold, Ruedi, Venkitaraman, Ashok R., Wickramasinghe, Vihandha O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554779/ https://www.ncbi.nlm.nih.gov/pubmed/28768205 http://dx.doi.org/10.1016/j.celrep.2017.07.025 |
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