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Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids

Uterine fibroids (UF) are the most common pelvic tumors in women of reproductive-age and they usually cause heavy menstrual bleeding, pain and infertility. Autophagy is a collection of processes that enables the cells to digest and recycle their cytoplasmic contents, such as toxic protein aggregates...

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Detalles Bibliográficos
Autores principales: Andaloussi, Abdeljabar El, Habib, Samar, Soylemes, Gizem, Laknaur, Archana, Elhusseini, Heba, Al-Hendy, Ayman, Ismail, Nahed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554887/
https://www.ncbi.nlm.nih.gov/pubmed/28815060
http://dx.doi.org/10.1038/cddiscovery.2017.41