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Inhibition of mTOR signaling Confers Protection against Cerebral Ischemic Injury in Acute Hyperglycemic Rats

Hyperglycemia is known to exacerbate neuronal death resulted from cerebral ischemia. The mechanisms are not fully understood. The mammalian target of rapamycin (mTOR) pathway regulates cell growth, division and apoptosis. Recent studies suggest that activation of mTOR may mediate ischemic brain dama...

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Detalles Bibliográficos
Autores principales: Hei, Changchun, Liu, Ping, Yang, Xiao, Niu, Jianguo, Li, P. Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555105/
https://www.ncbi.nlm.nih.gov/pubmed/28808420
http://dx.doi.org/10.7150/ijbs.18976