Bromodomain and extraterminal inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps

Lytic infection by the Epstein-Barr virus (EBV) poses numerous health risks, such as infectious mononucleosis and lymphoproliferative disorder. Proteins in the bromodomain and extraterminal (BET) family regulate multiple stages of viral life cycles and provide promising intervention targets. Synthet...

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Detalles Bibliográficos
Autores principales: Keck, Kristin M., Moquin, Stephanie A., He, Amanda, Fernandez, Samantha G., Somberg, Jessica J., Liu, Stephanie M., Martinez, Delsy M., Miranda, JJ L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555189/
https://www.ncbi.nlm.nih.gov/pubmed/28588024
http://dx.doi.org/10.1074/jbc.M116.751644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555189/
https://www.ncbi.nlm.nih.gov/pubmed/28588024
http://dx.doi.org/10.1074/jbc.M116.751644

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