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Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome

Loss-of-function mutations in SCN1A cause Dravet syndrome (DS), a catastrophic childhood epilepsy in which patients experience comorbid behavioral conditions, including movement disorders, sleep abnormalities, anxiety, and intellectual disability. To study the functional consequences of voltage-gate...

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Detalles Bibliográficos
Autores principales: Grone, Brian P., Qu, Tiange, Baraban, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555352/
https://www.ncbi.nlm.nih.gov/pubmed/28812061
http://dx.doi.org/10.1523/ENEURO.0066-17.2017