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Human desmoid fibroblasts: matrix metalloproteinases, their inhibitors and modulation by Toremifene

BACKGROUND: Desmoid tumour is a benign, non metastasising neoplasm characterised by an elevated deposition of organic macromolecules in the extracellular matrix (ECM). The matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases involved in the degradation of ECM macromolecules. T...

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Detalles Bibliográficos
Autores principales: Balducci, Chiara, Lilli, Cinzia, Stabellini, Giordano, Marinucci, Lorella, Giustozzi, Giammario, Becchetti, Alessio, Cagini, Lucio, Locci, Paola
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555538/
https://www.ncbi.nlm.nih.gov/pubmed/15740610
http://dx.doi.org/10.1186/1471-2407-5-22