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Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitors

BACKGROUND: Surrogate measures for cardiovascular disease events have the potential to increase greatly the efficiency of clinical trials. A leading candidate for such a surrogate is the progression of intima-media thickness (IMT) of the carotid artery; much experience has been gained with this endp...

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Detalles Bibliográficos
Autores principales: Espeland, Mark A, O'Leary, Daniel H, Terry, James G, Morgan, Timothy, Evans, Greg, Mudra, Harald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555546/
https://www.ncbi.nlm.nih.gov/pubmed/15760471
http://dx.doi.org/10.1186/1468-6708-6-3