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Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression
Expression quantitative trait locus (eQTL) detection has emerged as an important tool for unraveling of the relationship between genetic risk factors and disease or clinical phenotypes. Most studies use single marker linear regression to discover primary signals, followed by sequential conditional m...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555460/ https://www.ncbi.nlm.nih.gov/pubmed/28600440 http://dx.doi.org/10.1534/g3.117.043752 |