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Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression

Expression quantitative trait locus (eQTL) detection has emerged as an important tool for unraveling of the relationship between genetic risk factors and disease or clinical phenotypes. Most studies use single marker linear regression to discover primary signals, followed by sequential conditional m...

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Detalles Bibliográficos
Autores principales: Zeng, Biao, Lloyd-Jones, Luke R., Holloway, Alexander, Marigorta, Urko M., Metspalu, Andres, Montgomery, Grant W., Esko, Tonu, Brigham, Kenneth L., Quyyumi, Arshed A., Idaghdour, Youssef, Yang, Jian, Visscher, Peter M., Powell, Joseph E., Gibson, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555460/
https://www.ncbi.nlm.nih.gov/pubmed/28600440
http://dx.doi.org/10.1534/g3.117.043752