Secondary structure in the target as a confounding factor in synthetic oligomer microarray design

BACKGROUND: Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes. It is frequently assumed that eliminating self-complementarity, or screening for secondary structure in the probe, is sufficient to avoid i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ratushna, Vladyslava G, Weller, Jennifer W, Gibas, Cynthia J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555549/
https://www.ncbi.nlm.nih.gov/pubmed/15755320
http://dx.doi.org/10.1186/1471-2164-6-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555549/
https://www.ncbi.nlm.nih.gov/pubmed/15755320
http://dx.doi.org/10.1186/1471-2164-6-31

Ejemplares similares