Cargando…
Secondary structure in the target as a confounding factor in synthetic oligomer microarray design
BACKGROUND: Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes. It is frequently assumed that eliminating self-complementarity, or screening for secondary structure in the probe, is sufficient to avoid i...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555549/ https://www.ncbi.nlm.nih.gov/pubmed/15755320 http://dx.doi.org/10.1186/1471-2164-6-31 |