– (-) Menthol Induces Reversal of Promoter Hypermethylation and Associated Up-Regulation of the FANCF Gene in the SiHa Cell Line

OBJECTIVE: To identify natural bioactive molecules with potential to inhibit DNA methyltransferase 1 (DNMT1) and cause reactivation of genes silenced due to promoter hypermethylation. METHODS AND RESULTS: -(-) Menthol and epigallocatechin-3-gallate (EGCG) (reference molecule) were investigated using...

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Detalles Bibliográficos
Autores principales: Parashar, Gaurav, Parashar, Nidarshana Chaturvedi, Capalash, Neena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555548/
https://www.ncbi.nlm.nih.gov/pubmed/28612587
http://dx.doi.org/10.22034/APJCP.2017.18.5.1365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555548/
https://www.ncbi.nlm.nih.gov/pubmed/28612587
http://dx.doi.org/10.22034/APJCP.2017.18.5.1365

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