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Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase

The complement cascade is crucial for clearance and control of invading pathogens, and as such is a key target for pathogen mediated host modulation. C3 is the central molecule of the complement cascade, and plays a vital role in opsonization of bacteria and recruitment of neutrophils to the site of...

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Detalles Bibliográficos
Autores principales: Lynskey, Nicola N., Reglinski, Mark, Calay, Damien, Siggins, Matthew K., Mason, Justin C., Botto, Marina, Sriskandan, Shiranee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555575/
https://www.ncbi.nlm.nih.gov/pubmed/28806402
http://dx.doi.org/10.1371/journal.ppat.1006493