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Chronic In Vivo Interaction of Dendritic Cells Expressing the Ligand Rae-1ε with NK Cells Impacts NKG2D Expression and Function

To investigate how dendritic cells (DCs) interact with NK cells in vivo, we developed a novel mouse model in which Rae-1ε, a ligand of the NKG2D receptor, is expressed in cells with high levels of CD11c. In these CD11c-Rae1 mice, expression of Rae-1 was confirmed on all subsets of DCs and a small su...

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Detalles Bibliográficos
Autores principales: Morvan, Maelig G., Champsaur, Marine, Reizis, Boris, Lanier, Lewis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555644/
https://www.ncbi.nlm.nih.gov/pubmed/28815225
http://dx.doi.org/10.4049/immunohorizons.1700004