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Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out mice
BACKGROUND: CpG oligodeoxynucleotides (CpG-ODN) are capable of inducing high amounts of type I IFNs with many immunomodulatory properties. Furthermore, type-I IFNs have been proposed to play a key role in mediating effects of CpG-ODN. The precise role of IFN-β in the immunomodulatory effects of CpG-...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555575/ https://www.ncbi.nlm.nih.gov/pubmed/15748290 http://dx.doi.org/10.1186/1465-9921-6-25 |