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Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats

Topiroxostat is a novel inhibitor of xanthine oxidase, and is postulated to exert a renoprotective effect. Puromycin aminonucleoside nephrosis (PAN) is a rat model of minimal change nephrotic syndrome. In this study, we examined whether topiroxostat ameliorates the kidney injury in PAN rats that was...

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Detalles Bibliográficos
Autores principales: Kawamorita, Yosuke, Shiraishi, Takeshi, Tamura, Yoshifuru, Kumagai, Takanori, Shibata, Shigeru, Fujigaki, Yoshihide, Hosoyamada, Makoto, Nakagawa, Takahiko, Uchida, Shunya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555887/
https://www.ncbi.nlm.nih.gov/pubmed/28774949
http://dx.doi.org/10.14814/phy2.13358