The proteasome deubiquitinase inhibitor b-AP15 enhances DR5 activation-induced apoptosis through stabilizing DR5

b-AP15 and its derivatives block proteasome deubiquitinase (DUB) activity and have been developed and tested in the clinic as potential cancer therapeutic agents. b-AP15 induces apoptosis in cancer cells, but the underlying mechanisms are largely undefined. The current study focuses on studying the...

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Detalles Bibliográficos
Autores principales: Oh, You-Take, Deng, Liang, Deng, Jiusheng, Sun, Shi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556018/
https://www.ncbi.nlm.nih.gov/pubmed/28808321
http://dx.doi.org/10.1038/s41598-017-08424-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556018/
https://www.ncbi.nlm.nih.gov/pubmed/28808321
http://dx.doi.org/10.1038/s41598-017-08424-w

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