Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

The glucocorticoid receptor (GR) is a transcription factor of which the underlying gene regulatory mechanisms are complex and incompletely understood. The non-steroidal anti-inflammatory Compound A (CpdA), a selective GR modulating compound in various cell models, has been shown to favour GR-mediate...

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Detalles Bibliográficos
Autores principales: Desmet, S. J., Bougarne, N., Van Moortel, L., De Cauwer, L., Thommis, J., Vuylsteke, M., Ratman, D., Houtman, R., Tavernier, J., De Bosscher, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556032/
https://www.ncbi.nlm.nih.gov/pubmed/28808239
http://dx.doi.org/10.1038/s41598-017-07941-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556032/
https://www.ncbi.nlm.nih.gov/pubmed/28808239
http://dx.doi.org/10.1038/s41598-017-07941-y

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