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Atomic Force Microscopy micro-rheology reveals large structural inhomogeneities in single cell-nuclei

During growth, differentiation and migration of cells, the nucleus changes size and shape, while encountering forces generated by the cell itself and its environment. Although there is increasing evidence that such mechanical signals are employed to control gene expression, it remains unclear how me...

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Detalles Bibliográficos
Autores principales: Lherbette, Michael, dos Santos, Ália, Hari-Gupta, Yukti, Fili, Natalia, Toseland, Christopher P., Schaap, Iwan A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556037/
https://www.ncbi.nlm.nih.gov/pubmed/28808261
http://dx.doi.org/10.1038/s41598-017-08517-6