Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors

Development of neural progenitors depends upon the coordination of appropriate intrinsic responses to extrinsic signalling pathways. Here we show the deubiquitylating enzyme, Usp9x regulates components of both intrinsic and extrinsic fate determinants. Nestin-cre mediated ablation of Usp9x from embr...

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Detalles Bibliográficos
Autores principales: Premarathne, Susitha, Murtaza, Mariyam, Matigian, Nicholas, Jolly, Lachlan A., Wood, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556043/
https://www.ncbi.nlm.nih.gov/pubmed/28808228
http://dx.doi.org/10.1038/s41598-017-05451-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556043/
https://www.ncbi.nlm.nih.gov/pubmed/28808228
http://dx.doi.org/10.1038/s41598-017-05451-5

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