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Generation and characterization of a mouse line for monitoring translation in dopaminergic neurons

We developed a mouse line targeting midbrain dopamine neurons for Translating Ribosome Affinity Purification(TRAP). Here, we briefly report on the basic characterization of this mouse line including confirmation of expression of the transgene in midbrain dopamine neurons and validation of its effect...

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Detalles Bibliográficos
Autor principal: Dougherty, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556054/
https://www.ncbi.nlm.nih.gov/pubmed/28808330
http://dx.doi.org/10.1038/s41598-017-08618-2