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Gene editing in clinical isolates of Candida parapsilosis using CRISPR/Cas9
Candida parapsilosis is one of the most common causes of candidiasis, particularly in the very young and the very old. Studies of gene function are limited by the lack of a sexual cycle, the diploid genome, and a paucity of molecular tools. We describe here the development of a plasmid-based CRISPR-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556056/ https://www.ncbi.nlm.nih.gov/pubmed/28808289 http://dx.doi.org/10.1038/s41598-017-08500-1 |