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Structure formation during translocon-unassisted co-translational membrane protein folding

Correctly folded membrane proteins underlie a plethora of cellular processes, but little is known about how they fold. Knowledge of folding mechanisms centres on reversible folding of chemically denatured membrane proteins. However, this cannot replicate the unidirectional elongation of the protein...

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Detalles Bibliográficos
Autores principales: Harris, Nicola J., Reading, Eamonn, Ataka, Kenichi, Grzegorzewski, Lucjan, Charalambous, Kalypso, Liu, Xia, Schlesinger, Ramona, Heberle, Joachim, Booth, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556060/
https://www.ncbi.nlm.nih.gov/pubmed/28808343
http://dx.doi.org/10.1038/s41598-017-08522-9