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LC3A Silencing Hinders Aggresome Vimentin Cage Clearance in Primary Choroid Plexus Carcinoma

Aggresomes are transient microtubule-dependent inclusion bodies that sequester misfolded proteins and are ultimately removed by autophagy. Here we report the generation of a choroid plexus carcinoma cell line; Children’s Cancer Hospital Egypt (CCHE)-45, which is characterized by the constitutive for...

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Detalles Bibliográficos
Autores principales: Nassar, Marwa, Samaha, Heba, Ghabriel, Myret, Yehia, Maha, Taha, Hala, Salem, Sherin, Shaaban, Khaled, Omar, Mariam, Ahmed, Nabil, El-Naggar, Shahenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556083/
https://www.ncbi.nlm.nih.gov/pubmed/28808307
http://dx.doi.org/10.1038/s41598-017-07403-5