Cargando…

LC3A Silencing Hinders Aggresome Vimentin Cage Clearance in Primary Choroid Plexus Carcinoma

Aggresomes are transient microtubule-dependent inclusion bodies that sequester misfolded proteins and are ultimately removed by autophagy. Here we report the generation of a choroid plexus carcinoma cell line; Children’s Cancer Hospital Egypt (CCHE)-45, which is characterized by the constitutive for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nassar, Marwa, Samaha, Heba, Ghabriel, Myret, Yehia, Maha, Taha, Hala, Salem, Sherin, Shaaban, Khaled, Omar, Mariam, Ahmed, Nabil, El-Naggar, Shahenda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556083/ https://www.ncbi.nlm.nih.gov/pubmed/28808307 http://dx.doi.org/10.1038/s41598-017-07403-5

Ejemplares similares

Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma
por: Taha, Hala, et al.
Publicado: (2015)

Aggresomes predict poor outcomes and implicate proteostasis in the pathogenesis of pediatric choroid plexus tumors
por: Amer, Nada, et al.
Publicado: (2021)

Association of Aggresomes with Survival Outcomes in Pediatric Medulloblastoma
por: Yehia, Maha, et al.
Publicado: (2019)

Computational comparative analysis identifies potential stemness-related markers for mesenchymal stromal/stem cells
por: Ghabriel, Myret, et al.
Publicado: (2023)

Accumulation of Endogenous LITAF in Aggresomes
por: Eaton, Heather E., et al.
Publicado: (2012)

Corneal keratin aggresome (CKAGG) formation and clearance by proteasome activation
por: Bardag-Gorce, Fawzia, et al.
Publicado: (2018)

Hook2 contributes to aggresome formation
por: Szebenyi, Györgyi, et al.
Publicado: (2007)

Caveolin-1 is an aggresome-inducing protein
por: Tiwari, Ajit, et al.
Publicado: (2016)

An inhibitor of ubiquitin conjugation and aggresome formation
por: An, Heeseon, et al.
Publicado: (2015)

Aggresomes Resemble Sites Specialized for Virus Assembly
por: Heath, Colin M., et al.
Publicado: (2001)

Aggresomes: A Cellular Response to Misfolded Proteins
por: Johnston, Jennifer A., et al.
Publicado: (1998)

C-terminally mutated tubby protein accumulates in aggresomes
por: Kim, Sunshin, et al.
Publicado: (2017)

Characterization and Dynamics of Aggresome Formation by a Cytosolic Gfp-Chimera✪
por: García-Mata, Rafael, et al.
Publicado: (1999)

Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes
por: Zhang, Xingqian, et al.
Publicado: (2011)

Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome
por: Iqbal, Anila, et al.
Publicado: (2020)

Adult fibroblasts use aggresomes only in distinct cell-states
por: Morrow, Christopher S., et al.
Publicado: (2022)

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment
por: Pilecka, Iwona, et al.
Publicado: (2011)

Aggresome formation is regulated by RanBPM through an interaction with HDAC6
por: Salemi, Louisa M., et al.
Publicado: (2014)

Characterization of aggregate/aggresome structures formed by polyhedrin of Bombyx mori nucleopolyhedrovirus
por: Guo, Zhong-Jian, et al.
Publicado: (2015)

Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer’s Disease
por: Rahman, Md. Ataur, et al.
Publicado: (2022)

Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma
por: Kassab, Shaymaa E., et al.
Publicado: (2019)

Transcriptomic Analysis Revealed an Emerging Role of Alternative Splicing in Embryonal Tumor with Multilayered Rosettes
por: Hesham, Dina, et al.
Publicado: (2020)

Vimentin and Anti Vimentin Antibodies in Chagas' Disease
por: Nascimento, Marilda Savoia, et al.
Publicado: (2018)

Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration
por: Cheema, Muhammad Umar, et al.
Publicado: (2014)

Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex
por: Park, Joori, et al.
Publicado: (2017)

Mitochondrial carrier protein overloading and misfolding induce aggresomes and proteostatic adaptations in the cytosol
por: Liu, Yaxin, et al.
Publicado: (2019)

Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition
por: Qin, Siyue, et al.
Publicado: (2019)

A protocol to visualize cytosolic aggresome-like bodies using confocal microscopy
por: Kim, Soyeon, et al.
Publicado: (2021)

HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent
por: Wang, Longlong, et al.
Publicado: (2023)

Caisse de pension du CERN: "non aux hedges funds"
por: Zaki, Myret
Publicado: (2006)

Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells
por: Beaudoin, Simon, et al.
Publicado: (2008)

Trapping of normal EB1 ligands in aggresomes formed by an EB1 deletion mutant
por: Riess, Nick P, et al.
Publicado: (2005)

Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation
por: Xu, Yiliang, et al.
Publicado: (2015)

ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity
por: Gerhardt, Maximilian J, et al.
Publicado: (2017)

USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis
por: Takahashi, Masahiko, et al.
Publicado: (2018)

Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes
por: Choi, Won Hoon, et al.
Publicado: (2020)

Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation
por: Park, Yeonkyoung, et al.
Publicado: (2020)

Vocal Hinderances
por: Hubbard, Dwight L.
Publicado: (1899)

The E3-Ubiquitin Ligase TRIM50 Interacts with HDAC6 and p62, and Promotes the Sequestration and Clearance of Ubiquitinated Proteins into the Aggresome
por: Fusco, Carmela, et al.
Publicado: (2012)

Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini
por: Ouyang, Hui, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_131604mbvgisjkkra52htu0454