NLRP3 inflammasome activation results in liver inflammation and fibrosis in mice infected with Schistosoma japonicum in a Syk-dependent manner

Granulomatous and fibrosing inflammation in response to soluble egg antigen (SEA) from Schistosoma japonicum (S. japonicum) is the main pathological process of S. japonicum infection. Inflammasome activation has recently been implicated in the pathogenesis of liver disease. However, the role of infl...

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Detalles Bibliográficos
Autores principales: Lu, Ya-Qi, Zhong, Shan, Meng, Nan, Fan, Yin-Ping, Tang, Wang-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556086/
https://www.ncbi.nlm.nih.gov/pubmed/28808303
http://dx.doi.org/10.1038/s41598-017-08689-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556086/
https://www.ncbi.nlm.nih.gov/pubmed/28808303
http://dx.doi.org/10.1038/s41598-017-08689-1

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