In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [(11)C]SNAP-7941 and [(18)F]FE@SNAP reveal specific uptake in the ventricular system

The MCHR1 is involved in the regulation of energy homeostasis and changes of the expression are linked to a variety of associated diseases, such as diabetes and adiposity. The study aimed at the in vitro and in vivo evaluation of [(11)C]SNAP-7941 and [(18)F]FE@SNAP as potential PET-tracers for the M...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeilinger, Markus, Dumanic, Monika, Pichler, Florian, Budinsky, Lubos, Wadsak, Wolfgang, Pallitsch, Katharina, Spreitzer, Helmut, Lanzenberger, Rupert, Hacker, Marcus, Mitterhauser, Markus, Philippe, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556108/
https://www.ncbi.nlm.nih.gov/pubmed/28808288
http://dx.doi.org/10.1038/s41598-017-08684-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556108/
https://www.ncbi.nlm.nih.gov/pubmed/28808288
http://dx.doi.org/10.1038/s41598-017-08684-6

Ejemplares similares