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In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [(11)C]SNAP-7941 and [(18)F]FE@SNAP reveal specific uptake in the ventricular system
The MCHR1 is involved in the regulation of energy homeostasis and changes of the expression are linked to a variety of associated diseases, such as diabetes and adiposity. The study aimed at the in vitro and in vivo evaluation of [(11)C]SNAP-7941 and [(18)F]FE@SNAP as potential PET-tracers for the M...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556108/ https://www.ncbi.nlm.nih.gov/pubmed/28808288 http://dx.doi.org/10.1038/s41598-017-08684-6 |