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Genetic Factors Influencing Drug-Induced Liver Injury: Do They Have a Role in Prevention and Diagnosis?

PURPOSE OF REVIEW: The pathogenesis of DILI is currently unknown; however, research has shown strong genetic associations with some DILIs. This paper describes the variant alleles uncovered by GWAS and discusses their potential role as susceptibility biomarkers. RECENT FINDINGS: An association with...

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Detalles Bibliográficos
Autores principales: Clare, Kathleen E., Miller, Michael H., Dillon, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556130/
https://www.ncbi.nlm.nih.gov/pubmed/28856081
http://dx.doi.org/10.1007/s11901-017-0363-9