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Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

Tumor progression alters the composition and physical properties of the extracellular matrix. Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis. While endothelial cells are key players in cancer progression, the influence of tumor stiffness on the endotheli...

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Detalles Bibliográficos
Autores principales: Reid, Steven E, Kay, Emily J, Neilson, Lisa J, Henze, Anne‐Theres, Serneels, Jens, McGhee, Ewan J, Dhayade, Sandeep, Nixon, Colin, Mackey, John BG, Santi, Alice, Swaminathan, Karthic, Athineos, Dimitris, Papalazarou, Vasileios, Patella, Francesca, Román‐Fernández, Álvaro, ElMaghloob, Yasmin, Hernandez‐Fernaud, Juan Ramon, Adams, Ralf H, Ismail, Shehab, Bryant, David M, Salmeron‐Sanchez, Manuel, Machesky, Laura M, Carlin, Leo M, Blyth, Karen, Mazzone, Massimiliano, Zanivan, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556271/
https://www.ncbi.nlm.nih.gov/pubmed/28694244
http://dx.doi.org/10.15252/embj.201694912