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Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice

Hereditary hemochromatosis and iron imbalance are associated with susceptibility to bacterial infection; however, the underlying mechanisms are poorly understood. Here, we performed in vivo bacterial infection screening using several mouse models of hemochromatosis, including Hfe (Hfe(−/−)), hemojuv...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Shen, Yuanyuan, Tao, Yunlong, Wei, Jiayu, Wang, Hao, An, Peng, Zhang, Zhuzhen, Gao, Hong, Zhou, Tianhua, Wang, Fudi, Min, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556331/
https://www.ncbi.nlm.nih.gov/pubmed/28815056
http://dx.doi.org/10.1038/celldisc.2017.28