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Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix

BACKGROUND: Mesenchymal stem cell therapy for osteoarthritis (OA) has been widely investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of genetic information have been implicated in many diseases and are known to participate in many physiological processes. Here, we in...

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Detalles Bibliográficos
Autores principales: Wang, Yafei, Yu, Dongsheng, Liu, Zhiming, Zhou, Fang, Dai, Jun, Wu, Bingbing, Zhou, Jing, Heng, Boon Chin, Zou, Xiao Hui, Ouyang, Hongwei, Liu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556343/
https://www.ncbi.nlm.nih.gov/pubmed/28807034
http://dx.doi.org/10.1186/s13287-017-0632-0