Tumor-derived exosomes induce CD8(+) T cell suppressors

BACKGROUND: The suppressive nature of immune cells in the tumor microenvironment plays a major role in regulating anti-tumor immune responses. Our previous work demonstrated that a soluble factor from tumor cells is able to induce a suppressor phenotype (SP) in human CD8(+) T cells typified by loss...

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Detalles Bibliográficos
Autores principales: Maybruck, Brian T., Pfannenstiel, Lukas W., Diaz-Montero, Marcela, Gastman, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556362/
https://www.ncbi.nlm.nih.gov/pubmed/28806909
http://dx.doi.org/10.1186/s40425-017-0269-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556362/
https://www.ncbi.nlm.nih.gov/pubmed/28806909
http://dx.doi.org/10.1186/s40425-017-0269-7

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