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A method of decision analysis quantifying the effects of age and comorbidities on the probability of deriving significant benefit from medical treatments

BACKGROUND: The external validity, or generalizability, of trials and guidelines has been considered poor in the context of multiple morbidity. How multiple morbidity might affect the magnitude of benefit of a given treatment, and thereby external validity, has had little study. OBJECTIVE: To provid...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Stephen P., Bean, Nigel G., Ruberu, Ravi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Swiss Medical Press GmbH 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556438/
https://www.ncbi.nlm.nih.gov/pubmed/29090189
http://dx.doi.org/10.15256/joc.2017.7.93