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Connectivity, not region-intrinsic properties, predicts regional vulnerability to progressive tau pathology in mouse models of disease

Spatiotemporal tau pathology progression is regarded as highly stereotyped within each type of degenerative condition. For instance, AD has a progression of tau pathology consistently beginning in the entorhinal cortex, the locus coeruleus, and other nearby noradrenergic brainstem nuclei, before spr...

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Detalles Bibliográficos
Autores principales:	Mezias, Chris, LoCastro, Eve, Xia, Chuying, Raj, Ashish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556602/ https://www.ncbi.nlm.nih.gov/pubmed/28807028 http://dx.doi.org/10.1186/s40478-017-0459-z

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