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Myelination is delayed during postnatal brain development in the mdx mouse model of Duchenne muscular dystrophy

BACKGROUND: In Duchenne muscular dystrophy (DMD), the loss of the dystrophin component of the dystrophin-glycoprotein complex (DGC) compromises plasma membrane integrity in skeletal muscle, resulting in extensive muscle degeneration. In addition, many DMD patients exhibit brain deficits in which the...

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Detalles Bibliográficos
Autores principales: Aranmolate, Azeez, Tse, Nathaniel, Colognato, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556620/
https://www.ncbi.nlm.nih.gov/pubmed/28806929
http://dx.doi.org/10.1186/s12868-017-0381-0